Statistical modeling of extracellular vesicle cargo to predict clinical trial outcomes for hypoplastic left heart syndrome

Cardiac-derived c-kit+ progenitor cells (CPCs) are under investigation in the CHILD phase I clinical trial (NCT03406884) for the treatment of hypoplastic left heart syndrome (HLHS). The therapeutic efficacy of CPCs can be attributed to the release of extracellular vesicles (EVs). To understand sourc...

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Detalles Bibliográficos
Autores principales: Hoffman, Jessica R., Park, Hyun-Ji, Bheri, Sruti, Platt, Manu O., Hare, Joshua M., Kaushal, Sunjay, Bettencourt, Judith L., Lai, Dejian, Slesnick, Timothy C., Mahle, William T., Davis, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589850/
https://www.ncbi.nlm.nih.gov/pubmed/37868626
http://dx.doi.org/10.1016/j.isci.2023.107980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589850/
https://www.ncbi.nlm.nih.gov/pubmed/37868626
http://dx.doi.org/10.1016/j.isci.2023.107980

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