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Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases

Myelin defects cause a collection of myelin disorders in the brain. The lack of human models has limited us from better understanding pathological mechanisms of myelin diseases. While human induced pluripotent stem cell (hiPSC)-derived spheroids or organoids have been used to study brain development...

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Detalles Bibliográficos
Autores principales: Feng, Lizhao, Chao, Jianfei, Zhang, Mingzi, Pacquing, Elizabeth, Hu, Weidong, Shi, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589867/
https://www.ncbi.nlm.nih.gov/pubmed/37867939
http://dx.doi.org/10.1016/j.isci.2023.108037