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Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases
Myelin defects cause a collection of myelin disorders in the brain. The lack of human models has limited us from better understanding pathological mechanisms of myelin diseases. While human induced pluripotent stem cell (hiPSC)-derived spheroids or organoids have been used to study brain development...
Autores principales: | Feng, Lizhao, Chao, Jianfei, Zhang, Mingzi, Pacquing, Elizabeth, Hu, Weidong, Shi, Yanhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589867/ https://www.ncbi.nlm.nih.gov/pubmed/37867939 http://dx.doi.org/10.1016/j.isci.2023.108037 |
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