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Optogenetic targeting of AII amacrine cells restores retinal computations performed by the inner retina

Most inherited retinal dystrophies display progressive photoreceptor cell degeneration leading to severe visual impairment. Optogenetic reactivation of inner retinal neurons is a promising avenue to restore vision in retinas having lost their photoreceptors. Expression of optogenetic proteins in sur...

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Detalles Bibliográficos
Autores principales: Khabou, Hanen, Orendorff, Elaine, Trapani, Francesco, Rucli, Marco, Desrosiers, Melissa, Yger, Pierre, Dalkara, Deniz, Marre, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589896/
https://www.ncbi.nlm.nih.gov/pubmed/37868206
http://dx.doi.org/10.1016/j.omtm.2023.09.003