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Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles

BACKGROUND: The pathogenesis of benign prostatic hyperplasia (BPH) has not been fully elucidated. Ras homology family member A (RhoA) plays an important role in regulating cell cytoskeleton, growth and fibrosis. The role of RhoA in BPH remains unclear. METHODS: This study aimed to clarify the expres...

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Detalles Bibliográficos
Autores principales: Shan, Shidong, Su, Min, Li, Yan, Wang, Zhen, Liu, Daoquan, Zhou, Yongying, Fu, Xun, Yang, Shu, Zhang, Junchao, Qiu, Jizhang, Liu, Huan, Zeng, Guang, Chen, Ping, Wang, Xinghuan, DiSanto, Michael E., Guo, Yuming, Zhang, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10589999/
https://www.ncbi.nlm.nih.gov/pubmed/37864185
http://dx.doi.org/10.1186/s10020-023-00734-2