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SPIRAL: integrating and aligning spatially resolved transcriptomics data across different experiments, conditions, and technologies

Properly integrating spatially resolved transcriptomics (SRT) generated from different batches into a unified gene-spatial coordinate system could enable the construction of a comprehensive spatial transcriptome atlas. Here, we propose SPIRAL, consisting of two consecutive modules: SPIRAL-integratio...

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Detalles Bibliográficos
Autores principales: Guo, Tiantian, Yuan, Zhiyuan, Pan, Yan, Wang, Jiakang, Chen, Fengling, Zhang, Michael Q., Li, Xiangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590036/
https://www.ncbi.nlm.nih.gov/pubmed/37864231
http://dx.doi.org/10.1186/s13059-023-03078-6