Canagliflozin and irbesartan ameliorate renal fibrosis via the TGF-β1/Smad signaling pathway in Dahl salt-sensitive rats

OBJECTIVES: This study assessed the antifibrotic effects of canagliflozin, with or without irbesartan, on renal injury in Dahl salt-sensitive (SS) rats fed a high-salt (HS) diet. METHODS: After the preconditioning stage, Dahl SS rats (n = 47) were divided into five experimental groups as follows: lo...

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Detalhes bibliográficos
Principais autores: Zhai, Jianlong, Wang, Zhongli, Zhang, Tingting, He, Lili, Ma, Sai, Zuo, Qingjuan, Zhang, Guorui, Wang, Xinyu, Guo, Yifang
Formato: Online Atigo Texto
Idioma:English
Publicado em: SAGE Publications 2023
Assuntos:
Pre-Clinical Research Report
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590049/
https://www.ncbi.nlm.nih.gov/pubmed/37862678
http://dx.doi.org/10.1177/03000605231206289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590049/
https://www.ncbi.nlm.nih.gov/pubmed/37862678
http://dx.doi.org/10.1177/03000605231206289

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