Variant enterovirus A71 found in immune-suppressed patient binds to heparan sulfate and exhibits neurotropism in B-cell-depleted mice

Enterovirus A71 (EV-A71) causes hand, foot, and mouth disease outbreaks with neurological complications and deaths. We previously isolated an EV-A71 variant in the stool, cerebrospinal fluid, and blood of an immunocompromised patient who had a leucine-to-arginine substitution on the VP1 capsid prote...

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Detalles Bibliográficos
Autores principales: Weng, Kuo-Feng, Tee, Han Kang, Tseligka, Eirini D., Cagno, Valeria, Mathez, Gregory, Rosset, Stéphane, Nagamine, Claude M., Sarnow, Peter, Kirkegaard, Karla, Tapparel, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590055/
https://www.ncbi.nlm.nih.gov/pubmed/37058406
http://dx.doi.org/10.1016/j.celrep.2023.112389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590055/
https://www.ncbi.nlm.nih.gov/pubmed/37058406
http://dx.doi.org/10.1016/j.celrep.2023.112389

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