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Hypercontractile cardiac phenotype in mice overexpressing the regulatory subunit PR72 of protein phosphatase 2A

BACKGROUND: The activity, localization, and substrate specificity of the protein phosphatase 2A (PP2A) heterotrimer are controlled by various regulatory B subunits. PR72 belongs to the B'' gene family and has been shown to be upregulated in human heart failure. However, little is known abo...

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Detalles Bibliográficos
Autores principales: Herting, Julius R., König, Jule H., Hadova, Katarina, Heinick, Alexander, Müller, Frank U., Pauls, Paul, Seidl, Matthias D., Soppa, Carolina, Kirchhefer, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590119/
https://www.ncbi.nlm.nih.gov/pubmed/37868783
http://dx.doi.org/10.3389/fcvm.2023.1239555