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Hypercontractile cardiac phenotype in mice overexpressing the regulatory subunit PR72 of protein phosphatase 2A
BACKGROUND: The activity, localization, and substrate specificity of the protein phosphatase 2A (PP2A) heterotrimer are controlled by various regulatory B subunits. PR72 belongs to the B'' gene family and has been shown to be upregulated in human heart failure. However, little is known abo...
Autores principales: | Herting, Julius R., König, Jule H., Hadova, Katarina, Heinick, Alexander, Müller, Frank U., Pauls, Paul, Seidl, Matthias D., Soppa, Carolina, Kirchhefer, Uwe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590119/ https://www.ncbi.nlm.nih.gov/pubmed/37868783 http://dx.doi.org/10.3389/fcvm.2023.1239555 |
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