Cargando…

Long-term efficacy and safety of lerodalcibep in heterozygous familial hypercholesterolaemia: the LIBerate-HeFH trial

BACKGROUND AND AIMS: Lerodalcibep, a novel small recombinant fusion protein of a proprotein convertase subtilisin/kexin type 9 gene–binding domain (adnectin) and human serum albumin, demonstrated highly effective low-density lipoprotein cholesterol (LDL-C) reduction with monthly 300 mg in 1.2 mL sub...

Descripción completa

Detalles Bibliográficos
Autores principales: Raal, Frederick, Fourie, Nyda, Scott, Russell, Blom, Dirk, De Vries Basson, Matthys, Kayikcioglu, Meral, Caldwell, Kate, Kallend, David, Stein, Evan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590131/
https://www.ncbi.nlm.nih.gov/pubmed/37639462
http://dx.doi.org/10.1093/eurheartj/ehad596