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Sirtuin4 alleviates severe acute pancreatitis by regulating HIF-1α/HO-1 mediated ferroptosis

Acute pancreatitis (AP) is a common emergency of the digestive system and serious cases can develop into severe acute pancreatitis (SAP), which ortality rates up to 30%. Sirtuin4 (SIRT4) is a member of the sirtuin family, and plays a key role in inflammation and oxidative stress. However, the potent...

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Detalles Bibliográficos
Autores principales: Liu, Yanna, Cui, Huning, Mei, Chaopeng, Cui, Mengwei, He, Qianqian, Wang, Qiaofang, Li, Dejian, Song, Yaodong, Li, Jiye, Chen, Sanyang, Zhu, Changju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590376/
https://www.ncbi.nlm.nih.gov/pubmed/37865653
http://dx.doi.org/10.1038/s41419-023-06216-x