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Synthesis of novel coumarin-based thiosemicarbazones and their implications in diabetic management via in-vitro and in-silico approaches

Diabetes mellitus has a high prevalence rate and it has been deemed a severe chronic metabolic disorder with long-term complications. This research aimed to identify compounds that could potentially inhibit the vital metabolic enzyme α-glucosidase and thereby exert an anti-hyperglycemic effect. The...

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Detalles Bibliográficos
Autores principales: Zahra, Syeda Bakhtawar, Ullah, Saeed, Halim, Sobia Ahsan, Waqas, Muhammad, Huda, Noor Ul, Khan, Ajmal, Binsaleh, Ammena Y., El-kott, Attalla F., Hussain, Javid, Al-Harrasi, Ahmed, Shafiq, Zahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590377/
https://www.ncbi.nlm.nih.gov/pubmed/37865657
http://dx.doi.org/10.1038/s41598-023-44837-6