Protein citrullination and NET formation do not contribute to the pathology of A20/TNFAIP3 mutant mice

A20 serves as a critical brake on NF-κB-dependent inflammation. In humans, polymorphisms in or near the TNFAIP3/A20 gene have been linked to various inflammatory disorders, including systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). Experimental gene knockout studies in mice have con...

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Detalles Bibliográficos
Autores principales: Van Damme, Karel F. A., Hertens, Pieter, Martens, Arne, Gilis, Elisabeth, Priem, Dario, Bruggeman, Inge, Fossoul, Amelie, Declercq, Jozefien, Aegerter, Helena, Wullaert, Andy, Hochepied, Tino, Hoste, Esther, Vande Walle, Lieselotte, Lamkanfi, Mohamed, Savvides, Savvas N., Elewaut, Dirk, Lambrecht, Bart N., van Loo, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590390/
https://www.ncbi.nlm.nih.gov/pubmed/37865713
http://dx.doi.org/10.1038/s41598-023-45324-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590390/
https://www.ncbi.nlm.nih.gov/pubmed/37865713
http://dx.doi.org/10.1038/s41598-023-45324-8

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