Rare predicted loss of function alleles in Bassoon (BSN) are associated with obesity

Bassoon (BSN) is a component of a hetero-dimeric presynaptic cytomatrix protein that orchestrates neurotransmitter release with Piccolo (PCLO) from glutamatergic neurons throughout the brain. Heterozygous missense variants in BSN have previously been associated with neurodegenerative disorders in hu...

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Detalles Bibliográficos
Autores principales: Zhu, Na, LeDuc, Charles A., Fennoy, Ilene, Laferrère, Blandine, Doege, Claudia A., Shen, Yufeng, Chung, Wendy K., Leibel, Rudolph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590409/
https://www.ncbi.nlm.nih.gov/pubmed/37865656
http://dx.doi.org/10.1038/s41525-023-00376-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590409/
https://www.ncbi.nlm.nih.gov/pubmed/37865656
http://dx.doi.org/10.1038/s41525-023-00376-7

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