3D chromatin interactions involving Drosophila insulators are infrequent but preferential and arise before TADs and transcription

In mammals, insulators contribute to the regulation of loop extrusion to organize chromatin into topologically associating domains. In Drosophila the role of insulators in 3D genome organization is, however, under current debate. Here, we addressed this question by combining bioinformatics analysis...

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Detalles Bibliográficos
Autores principales: Messina, Olivier, Raynal, Flavien, Gurgo, Julian, Fiche, Jean-Bernard, Pancaldi, Vera, Nollmann, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590426/
https://www.ncbi.nlm.nih.gov/pubmed/37865700
http://dx.doi.org/10.1038/s41467-023-42485-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590426/
https://www.ncbi.nlm.nih.gov/pubmed/37865700
http://dx.doi.org/10.1038/s41467-023-42485-y

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