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3D chromatin interactions involving Drosophila insulators are infrequent but preferential and arise before TADs and transcription
In mammals, insulators contribute to the regulation of loop extrusion to organize chromatin into topologically associating domains. In Drosophila the role of insulators in 3D genome organization is, however, under current debate. Here, we addressed this question by combining bioinformatics analysis...
Autores principales: | Messina, Olivier, Raynal, Flavien, Gurgo, Julian, Fiche, Jean-Bernard, Pancaldi, Vera, Nollmann, Marcelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590426/ https://www.ncbi.nlm.nih.gov/pubmed/37865700 http://dx.doi.org/10.1038/s41467-023-42485-y |
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