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Empagliflozin induces the transcriptional program for nutrient homeostasis in skeletal muscle in normal mice

Sodium-glucose cotransporter 2 inhibitors (SGLT2i) improve heart failure (HF) outcomes across a range of patient characteristics. A hypothesis that SGLT2i induce metabolic change similar to fasting has recently been proposed to explain their profound clinical benefits. However, it remains unclear wh...

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Detalles Bibliográficos
Autores principales: Kawakami, Ryo, Matsui, Hiroki, Matsui, Miki, Iso, Tatsuya, Yokoyama, Tomoyuki, Ishii, Hideki, Kurabayashi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590450/
https://www.ncbi.nlm.nih.gov/pubmed/37865720
http://dx.doi.org/10.1038/s41598-023-45390-y