Cargando…
Empagliflozin induces the transcriptional program for nutrient homeostasis in skeletal muscle in normal mice
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) improve heart failure (HF) outcomes across a range of patient characteristics. A hypothesis that SGLT2i induce metabolic change similar to fasting has recently been proposed to explain their profound clinical benefits. However, it remains unclear wh...
Autores principales: | Kawakami, Ryo, Matsui, Hiroki, Matsui, Miki, Iso, Tatsuya, Yokoyama, Tomoyuki, Ishii, Hideki, Kurabayashi, Masahiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590450/ https://www.ncbi.nlm.nih.gov/pubmed/37865720 http://dx.doi.org/10.1038/s41598-023-45390-y |
Ejemplares similares
-
CD36 is indispensable for nutrient homeostasis and endurance exercise capacity during prolonged fasting
por: Iso, Tatsuya, et al.
Publicado: (2018) -
Exercise endurance capacity is markedly reduced due to impaired energy homeostasis during prolonged fasting in FABP4/5 deficient mice
por: Iso, Tatsuya, et al.
Publicado: (2019) -
Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts
por: Sunaga, Hiroaki, et al.
Publicado: (2019) -
Ketone body and FGF21 coordinately regulate fasting-induced oxidative stress response in the heart
por: Kawakami, Ryo, et al.
Publicado: (2022) -
Stearoyl-CoA Desaturase-1 (SCD1) Augments Saturated Fatty Acid-Induced Lipid Accumulation and Inhibits Apoptosis in Cardiac Myocytes
por: Matsui, Hiroki, et al.
Publicado: (2012)