The MYBL2–CCL2 axis promotes tumor progression and resistance to anti-PD-1 therapy in ovarian cancer by inducing immunosuppressive macrophages

BACKGROUND: An immunosuppressive tumor microenvironment in ovarian cancer facilitates tumor progression and resistance to immunotherapy. The function of MYB Proto-Oncogene Like 2 (MYBL2) in the tumor microenvironment remains largely unexplored. METHODS: A syngeneic intraovarian mouse model, flow cyt...

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Detalles Bibliográficos
Autores principales: Pan, Baoyue, Wan, Ting, Zhou, Yun, Huang, Shuting, Yuan, Linjing, Jiang, Yinan, Zheng, Xiaojing, Liu, Pingping, Xiang, Huiling, Ju, Mingxiu, Luo, Rongzhen, Jia, Weihua, Lan, ChunYan, Li, Jundong, Zheng, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590509/
https://www.ncbi.nlm.nih.gov/pubmed/37865750
http://dx.doi.org/10.1186/s12935-023-03079-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590509/
https://www.ncbi.nlm.nih.gov/pubmed/37865750
http://dx.doi.org/10.1186/s12935-023-03079-2

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