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In-cell Western assay to quantify infection with pathogenic orthohantavirus Puumala virus in replication kinetics and antiviral drug testing

Hemorrhagic fever with renal syndrome (HFRS) represents a serious zoonotic disease caused by orthohantaviruses in Eurasia. A specific antiviral therapy is not available. HFRS is characterized by acute kidney injury (AKI) with often massive proteinuria. Infection of kidney cells may contribute to the...

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Detalles Bibliográficos
Autores principales: Nusshag, Christian, Schreiber, Pamela, Uhrig, Josephine, Zeier, Martin, Krautkrämer, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590686/
https://www.ncbi.nlm.nih.gov/pubmed/37777116
http://dx.doi.org/10.1016/j.virusres.2023.199230