Nanobodies with cross-neutralizing activity provide prominent therapeutic efficacy in mild and severe COVID-19 rodent models

The weakened protective efficacy of COVID-19 vaccines and antibodies caused by SARS-CoV-2 variants presents a global health emergency, which underscores the urgent need for universal therapeutic antibody intervention for clinical patients. Here, we screened three alpacas-derived nanobodies (Nbs) wit...

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Detalles Bibliográficos
Autores principales: Han, Qiuxue, Wang, Shen, Wang, Zhenshan, Zhang, Cheng, Wang, Xinyue, Feng, Na, Wang, Tiecheng, Zhao, Yongkun, Chi, Hang, Yan, Feihu, Xia, Xianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590698/
https://www.ncbi.nlm.nih.gov/pubmed/37423308
http://dx.doi.org/10.1016/j.virs.2023.07.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590698/
https://www.ncbi.nlm.nih.gov/pubmed/37423308
http://dx.doi.org/10.1016/j.virs.2023.07.003

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