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Enterovirus D68 infection upregulates SOCS3 expression to inhibit JAK-STAT3 signaling and antagonize the innate interferon response of the host

Enterovirus D68 (EV-D68) can cause respiratory diseases and acute flaccid paralysis, posing a great threat to public health. Interferons are cytokines secreted by host cells that have broad-spectrum antiviral effects, inducing the expression of hundreds of interferon-stimulated genes (ISGs). EV-D68...

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Detalles Bibliográficos
Autores principales: Zhang, Yuling, Xu, Leling, Zhang, Zhe, Su, Xin, Wang, Zhiyun, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590701/
https://www.ncbi.nlm.nih.gov/pubmed/37657555
http://dx.doi.org/10.1016/j.virs.2023.08.007