Glutarate regulates T cell metabolism and anti-tumour immunity

T cell function and fate can be influenced by several metabolites: in some cases, acting through enzymatic inhibition of α-ketoglutarate-dependent dioxygenases, in others, through post-translational modification of lysines in important targets. We show here that glutarate, a product of amino acid ca...

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Detalles Bibliográficos
Autores principales: Minogue, Eleanor, Cunha, Pedro P., Wadsworth, Brennan J., Grice, Guinevere L., Sah-Teli, Shiv K., Hughes, Rob, Bargiela, David, Quaranta, Alessandro, Zurita, Javier, Antrobus, Robin, Velica, Pedro, Barbieri, Laura, Wheelock, Craig E., Koivunen, Peppi, Nathan, James A., Foskolou, Iosifina P., Johnson, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590756/
https://www.ncbi.nlm.nih.gov/pubmed/37605057
http://dx.doi.org/10.1038/s42255-023-00855-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590756/
https://www.ncbi.nlm.nih.gov/pubmed/37605057
http://dx.doi.org/10.1038/s42255-023-00855-2

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