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Uncovering distinct progression patterns of tau deposition in progressive supranuclear palsy using [(18)F]Florzolotau PET imaging and subtype/stage inference algorithm

BACKGROUND: Progressive supranuclear palsy (PSP) is a primary 4-repeat tauopathy with diverse clinical phenotypes. Previous post-mortem studies examined tau deposition sequences in PSP, but in vivo scrutiny is lacking. METHODS: We conducted [(18)F]Florzolotau tau positron emission tomography (PET) s...

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Detalles Bibliográficos
Autores principales: Hong, Jimin, Lu, Jiaying, Liu, Fengtao, Wang, Min, Li, Xinyi, Clement, Christoph, Lopes, Leonor, Brendel, Matthias, Rominger, Axel, Yen, Tzu-Chen, Guan, Yihui, Tian, Mei, Wang, Jian, Zuo, Chuantao, Shi, Kuangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590768/
https://www.ncbi.nlm.nih.gov/pubmed/37839135
http://dx.doi.org/10.1016/j.ebiom.2023.104835