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Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the predominant impairment of neurons in the hippocampus and the formation of amyloid plaques, hyperphosphorylated tau protein, and neurofibrillary tangles in the brain. The overexpression of amyloid-β precursor protein (APP)...

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Detalles Bibliográficos
Autores principales: Iyaswamy, Ashok, Thakur, Abhimanyu, Guan, Xin-Jie, Krishnamoorthi, Senthilkumar, Fung, Tsz Yan, Lu, Kejia, Gaurav, Isha, Yang, Zhijun, Su, Cheng-Fu, Lau, Kwok-Fai, Zhang, Kui, Ng, Roy Chun-Laam, Lian, Qizhou, Cheung, King-Ho, Ye, Keqiang, Chen, Huanhuan Joyce, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590775/
https://www.ncbi.nlm.nih.gov/pubmed/37867176
http://dx.doi.org/10.1038/s41392-023-01657-4