Scn2a insufficiency alters spontaneous neuronal Ca(2+) activity in somatosensory cortex during wakefulness

SCN2A protein-truncating variants (PTV) can result in neurological disorders such as autism spectrum disorder and intellectual disability, but they are less likely to cause epilepsy in comparison to missense variants. While in vitro studies showed PTV reduce action potential firing, consequences at...

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Detalles Bibliográficos
Autores principales: Li, Melody, Eltabbal, Mohamed, Tran, Hoang-Dai, Kuhn, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590963/
https://www.ncbi.nlm.nih.gov/pubmed/37876801
http://dx.doi.org/10.1016/j.isci.2023.108138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590963/
https://www.ncbi.nlm.nih.gov/pubmed/37876801
http://dx.doi.org/10.1016/j.isci.2023.108138

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