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aKmerBroom: Ancient oral DNA decontamination using Bloom filters on k-mer sets

Dental calculus samples are modeled as a mixture of DNA coming from dental plaque and contaminants. Current computational decontamination methods such as Recentrifuge and DeconSeq require either a reference database or sequenced negative controls, and therefore have limited use cases. We present a r...

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Detalles Bibliográficos
Autores principales: Duitama González, Camila, Rangavittal, Samarth, Vicedomini, Riccardo, Chikhi, Rayan, Richard, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590965/
https://www.ncbi.nlm.nih.gov/pubmed/37876815
http://dx.doi.org/10.1016/j.isci.2023.108057