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Microbiota-derived imidazole propionate inhibits type 2 diabetic skin wound healing by targeting SPNS2-mediated S1P transport

Imidazole propionate (ImP) is a recently discovered metabolite of T2DM-related gut microbiota. The effect of ImP on T2DM wound healing has not been studied yet. In this research, the changes of ImP-producing bacteria on the skin are firstly evaluated. 16sRNA sequencing results showed that the abunda...

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Detalles Bibliográficos
Autores principales: Zheng, Shaoting, Wang, Hongqi, Han, Jingxia, Dai, Xintong, Lv, Ying, Sun, Tao, Liu, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10590984/
https://www.ncbi.nlm.nih.gov/pubmed/37876799
http://dx.doi.org/10.1016/j.isci.2023.108092