Hyperglycemia-regulated tRNA-derived fragment tRF-3001a propels neurovascular dysfunction in diabetic mice

Neurovascular dysfunction is a preclinical manifestation of diabetic complications, including diabetic retinopathy (DR). Herein, we report that a transfer RNA-derived RNA fragment, tRF-3001a, is significantly upregulated under diabetic conditions. tRF-3001a downregulation inhibits Müller cell activa...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Jun-Ya, Yao, Wen, Ni, Xi-Sen, Yao, Mu-Di, Bai, Wen, Yang, Tian-Jing, Zhang, Zi-Ran, Li, Xiu-Miao, Jiang, Qin, Yan, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591036/
https://www.ncbi.nlm.nih.gov/pubmed/37757825
http://dx.doi.org/10.1016/j.xcrm.2023.101209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591036/
https://www.ncbi.nlm.nih.gov/pubmed/37757825
http://dx.doi.org/10.1016/j.xcrm.2023.101209

Ejemplares similares