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Hyperglycemia-regulated tRNA-derived fragment tRF-3001a propels neurovascular dysfunction in diabetic mice

Neurovascular dysfunction is a preclinical manifestation of diabetic complications, including diabetic retinopathy (DR). Herein, we report that a transfer RNA-derived RNA fragment, tRF-3001a, is significantly upregulated under diabetic conditions. tRF-3001a downregulation inhibits Müller cell activa...

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Detalles Bibliográficos
Autores principales:	Zhu, Jun-Ya, Yao, Wen, Ni, Xi-Sen, Yao, Mu-Di, Bai, Wen, Yang, Tian-Jing, Zhang, Zi-Ran, Li, Xiu-Miao, Jiang, Qin, Yan, Biao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591036/ https://www.ncbi.nlm.nih.gov/pubmed/37757825 http://dx.doi.org/10.1016/j.xcrm.2023.101209

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