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Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine

Although promising, dendritic cell (DC) vaccines still provide limited clinical benefits, mainly due to the immunosuppressive tumor microenvironment (TME) and the lack of tumor-associated antigens (TAAs). Oncolytic virus therapy is an ideal strategy to overcome immunosuppression and expose TAAs; the...

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Detalles Bibliográficos
Autores principales: Dan, Jia, Cai, Jing, Zhong, Yingqian, Wang, Chaoqun, Huang, Shanyu, Zeng, Ying, Fan, Zhen, Xu, Cuiying, Hu, Linyi, Zhang, Jiayu, Hu, Jun, Liu, Ying, Su, Xingwen, Zhu, Wenbo, Yan, Guangmei, Liang, Jiankai, Lin, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591054/
https://www.ncbi.nlm.nih.gov/pubmed/37820722
http://dx.doi.org/10.1016/j.xcrm.2023.101229