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Breaking barriers: NEK2 inhibition shines in multiple myeloma treatment

In their article, Cheng et al.(1) reveal that NEK2 loss reshapes the tumor microenvironment, reducing tumor-associated macrophages and decreasing T cell exhaustion. They show that this ultimately favors the immune system’s anti-cancer response in multiple myeloma.

Detalles Bibliográficos
Autores principales: Lischer, Christopher, Bruns, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591060/
https://www.ncbi.nlm.nih.gov/pubmed/37852178
http://dx.doi.org/10.1016/j.xcrm.2023.101237