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Unedited allogeneic iNKT cells show extended persistence in MHC-mismatched canine recipients

Allogeneic invariant natural killer T cells (allo-iNKTs) induce clinical remission in patients with otherwise incurable cancers and COVID-19-related acute respiratory failure. However, their functionality is inconsistent among individuals, and they become rapidly undetectable after infusion, raising...

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Detalles Bibliográficos
Autores principales: Rotolo, Antonia, Whelan, Eoin C., Atherton, Matthew J., Kulikovskaya, Irina, Jarocha, Danuta, Fraietta, Joseph A., Kim, Michele M., Diffenderfer, Eric S., Cengel, Keith A., Piviani, Martina, Radaelli, Enrico, Duran-Struuck, Raimon, Mason, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591065/
https://www.ncbi.nlm.nih.gov/pubmed/37852175
http://dx.doi.org/10.1016/j.xcrm.2023.101241