The kynurenine pathway presents multi-faceted metabolic vulnerabilities in cancer

The kynurenine pathway (KP) and associated catabolites play key roles in promoting tumor progression and modulating the host anti-tumor immune response. To date, considerable focus has been on the role of indoleamine 2,3-dioxygenase 1 (IDO1) and its catabolite, kynurenine (Kyn). However, increasing...

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Detalles Bibliográficos
Autores principales: León-Letelier, Ricardo A., Dou, Rongzhang, Vykoukal, Jody, Sater, Ali Hussein Abdel, Ostrin, Edwin, Hanash, Samir, Fahrmann, Johannes F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591110/
https://www.ncbi.nlm.nih.gov/pubmed/37876966
http://dx.doi.org/10.3389/fonc.2023.1256769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591110/
https://www.ncbi.nlm.nih.gov/pubmed/37876966
http://dx.doi.org/10.3389/fonc.2023.1256769

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