Functional genetic variation in pe/ppe genes contributes to diversity in Mycobacterium tuberculosis lineages and potential interactions with the human host

INTRODUCTION: Around 10% of the coding potential of Mycobacterium tuberculosisis constituted by two poorly understood gene families, the pe and ppe loci, thought to be involved in host-pathogen interactions. Their repetitive nature and high GC content have hindered sequence analysis, leading to excl...

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Detalles Bibliográficos
Autores principales: Gómez-González, Paula Josefina, Grabowska, Anna D., Tientcheu, Leopold D., Tsolaki, Anthony G., Hibberd, Martin L., Campino, Susana, Phelan, Jody E., Clark, Taane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591178/
https://www.ncbi.nlm.nih.gov/pubmed/37876785
http://dx.doi.org/10.3389/fmicb.2023.1244319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591178/
https://www.ncbi.nlm.nih.gov/pubmed/37876785
http://dx.doi.org/10.3389/fmicb.2023.1244319

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