Blastomeres of 8-cell mouse embryos differ in their ability to generate embryonic stem cells and produce lines with different transcriptional signatures

Embryonic stem cell (ESC) derivation from single blastomeres of 8-cell mouse embryos results in lower derivation rates than that from whole blastocysts, raising a biological question about the developmental potential of sister blastomeres. We aimed to assess the ability of 8-cell blastomeres to prod...

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Detalles Bibliográficos
Autores principales: Alonso-Alonso, Sandra, Esteve-Codina, Anna, Martin-Mur, Beatriz, Álvarez-González, Lucia, Ruiz-Herrera, Aurora, Santaló, Josep, Ibáñez, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591181/
https://www.ncbi.nlm.nih.gov/pubmed/37876553
http://dx.doi.org/10.3389/fcell.2023.1274660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591181/
https://www.ncbi.nlm.nih.gov/pubmed/37876553
http://dx.doi.org/10.3389/fcell.2023.1274660

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