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Macrocyclic Peptides Closed by a Thioether–Bipyridyl Unit That Grants Cell Membrane Permeability

[Image: see text] Membrane permeability is an important factor that determines the virtue of peptides targeting intracellular molecules. By introducing a membrane penetration motif, some peptides exhibit better membrane permeabilities. Previous choices for such motifs have usually been polycationic...

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Detalles Bibliográficos
Autores principales: Chen, Hongxue, Katoh, Takayuki, Suga, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591297/
https://www.ncbi.nlm.nih.gov/pubmed/37876498
http://dx.doi.org/10.1021/acsbiomedchemau.3c00027