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Modulation of the hippo-YAP pathway by cyclic stretch in rat type 2 alveolar epithelial cells—a proof-of-concept study

Background: Mechanical ventilation (MV) is a life supporting therapy but may also cause lung damage. This phenomenon is known as ventilator-induced lung injury (VILI). A potential pathomechanisms of ventilator-induced lung injury may be the stretch-induced production and release of cytokines and pro...

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Detalles Bibliográficos
Autores principales: Ran, Xi, Müller, Sabine, Brunssen, Coy, Huhle, Robert, Scharffenberg, Martin, Schnabel, Christian, Koch, Thea, Gama de Abreu, Marcelo, Morawietz, Henning, Ferreira, Jorge M. C., Wittenstein, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591329/
https://www.ncbi.nlm.nih.gov/pubmed/37877098
http://dx.doi.org/10.3389/fphys.2023.1253810