The Mechanism of Inhibition of Pyruvate Formate Lyase by Methacrylate

[Image: see text] Pyruvate Formate Lyase (PFL) catalyzes acetyl transfer from pyruvate to coenzyme a by a mechanism involving multiple amino acid radicals. A post-translationally installed glycyl radical (G(734)· in Escherichia coli) is essential for enzyme activity and two cysteines (C(418) and C(4...

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Detalles Bibliográficos
Autores principales: Cáceres, Juan Carlos, Dolmatch, August, Greene, Brandon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591478/
https://www.ncbi.nlm.nih.gov/pubmed/37797332
http://dx.doi.org/10.1021/jacs.3c07256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591478/
https://www.ncbi.nlm.nih.gov/pubmed/37797332
http://dx.doi.org/10.1021/jacs.3c07256

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