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The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation

Sphingolipids have key functions in membrane structure and cellular signaling. Ceramide is the central molecule of the sphingolipid metabolism and is generated by ceramide synthases (CerS) in the de novo pathway. Despite their critical function, mechanisms regulating CerS remain largely unknown. Usi...

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Detalles Bibliográficos
Autores principales: Boyd, Rowan A., Majumder, Saurav, Stiban, Johnny, Mavodza, Grace, Straus, Alexandra J., Kempelingaiah, Sachin K., Reddy, Varun, Hannun, Yusuf A., Obeid, Lina M., Senkal, Can E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591768/
https://www.ncbi.nlm.nih.gov/pubmed/37689067
http://dx.doi.org/10.1016/j.celrep.2023.113081