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The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
Sphingolipids have key functions in membrane structure and cellular signaling. Ceramide is the central molecule of the sphingolipid metabolism and is generated by ceramide synthases (CerS) in the de novo pathway. Despite their critical function, mechanisms regulating CerS remain largely unknown. Usi...
Autores principales: | Boyd, Rowan A., Majumder, Saurav, Stiban, Johnny, Mavodza, Grace, Straus, Alexandra J., Kempelingaiah, Sachin K., Reddy, Varun, Hannun, Yusuf A., Obeid, Lina M., Senkal, Can E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591768/ https://www.ncbi.nlm.nih.gov/pubmed/37689067 http://dx.doi.org/10.1016/j.celrep.2023.113081 |
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