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Metabolic transcriptomics dictate responses of cone photoreceptors to retinitis pigmentosa

Most mutations in retinitis pigmentosa (RP) arise in rod photoreceptors, but cone photoreceptors, responsible for high-resolution daylight and color vision, are subsequently affected, causing the most debilitating features of the disease. We used mass spectroscopy to follow (13)C metabolites deliver...

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Detalles Bibliográficos
Autores principales: Lee, Sang Joon, Emery, Douglas, Vukmanic, Eric, Wang, Yekai, Lu, Xiaoqin, Wang, Wei, Fortuny, Enzo, James, Robert, Kaplan, Henry J., Liu, Yongqing, Du, Jianhai, Dean, Douglas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591869/
https://www.ncbi.nlm.nih.gov/pubmed/37656622
http://dx.doi.org/10.1016/j.celrep.2023.113054