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CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance

The naked mole rat (NMR) is the longest-lived rodent, resistant to multiple age-related diseases including neurodegeneration. However, the mechanisms underlying the NMR’s resistance to neurodegenerative diseases remain elusive. Here, we isolated oligodendrocyte progenitor cells (OPCs) from NMRs and...

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Detalles Bibliográficos
Autores principales: Takasugi, Masaki, Ohtani, Naoko, Takemura, Kazuaki, Emmrich, Stephan, Zakusilo, Frances T., Yoshida, Yuya, Kutsukake, Nobuyuki, Mariani, John N., Windrem, Martha S., Chandler-Militello, Devin, Goldman, Steven A., Satoh, Junko, Ito, Shinji, Seluanov, Andrei, Gorbunova, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591879/
https://www.ncbi.nlm.nih.gov/pubmed/37708026
http://dx.doi.org/10.1016/j.celrep.2023.113130