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Statistical Assessment of Drug Synergy from In Vivo Combination Studies Using Mouse Tumor Models
Drug combination therapy is a promising strategy for treating cancer; however, its efficacy and synergy require rigorous evaluation in preclinical studies before going to clinical trials. Existing methods have limited power to detect synergy in animal studies. Here, we introduce a novel approach to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for Cancer Research
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10591909/ https://www.ncbi.nlm.nih.gov/pubmed/37830749 http://dx.doi.org/10.1158/2767-9764.CRC-23-0243 |