Chromatin accessibility in the Drosophila embryo is determined by transcription factor pioneering and enhancer activation

Chromatin accessibility is integral to the process by which transcription factors (TFs) read out cis-regulatory DNA sequences, but it is difficult to differentiate between TFs that drive accessibility and those that do not. Deep learning models that learn complex sequence rules provide an unpreceden...

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Detalles Bibliográficos
Autores principales: Brennan, Kaelan J., Weilert, Melanie, Krueger, Sabrina, Pampari, Anusri, Liu, Hsiao-yun, Yang, Ally W.H., Morrison, Jason A., Hughes, Timothy R., Rushlow, Christine A., Kundaje, Anshul, Zeitlinger, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592203/
https://www.ncbi.nlm.nih.gov/pubmed/37557175
http://dx.doi.org/10.1016/j.devcel.2023.07.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592203/
https://www.ncbi.nlm.nih.gov/pubmed/37557175
http://dx.doi.org/10.1016/j.devcel.2023.07.007

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