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Chromatin accessibility in the Drosophila embryo is determined by transcription factor pioneering and enhancer activation
Chromatin accessibility is integral to the process by which transcription factors (TFs) read out cis-regulatory DNA sequences, but it is difficult to differentiate between TFs that drive accessibility and those that do not. Deep learning models that learn complex sequence rules provide an unpreceden...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592203/ https://www.ncbi.nlm.nih.gov/pubmed/37557175 http://dx.doi.org/10.1016/j.devcel.2023.07.007 |