Nuclear translocation of an aminoacyl-tRNA synthetase may mediate a chronic “integrated stress response”

Various stress conditions are signaled through phosphorylation of translation initiation factor eukaryotic initiation factor 2α (eIF2α) to inhibit global translation while selectively activating transcription factor ATF4 to aid cell survival and recovery. However, this integrated stress response is...

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Detalles Bibliográficos
Autores principales: Jones, Julia A., Wei, Na, Cui, Haissi, Shi, Yi, Fu, Guangsen, Rauniyar, Navin, Shapiro, Ryan, Morodomi, Yosuke, Berenst, Nadine, Dumitru, Calin Dan, Kanaji, Sachiko, Yates, John R., Kanaji, Taisuke, Yang, Xiang-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592355/
https://www.ncbi.nlm.nih.gov/pubmed/37314928
http://dx.doi.org/10.1016/j.celrep.2023.112632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592355/
https://www.ncbi.nlm.nih.gov/pubmed/37314928
http://dx.doi.org/10.1016/j.celrep.2023.112632

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