Beyond matrix stiffness: targeting force-induced cancer drug resistance

During tumor progression, mechanical abnormalities in the tumor microenvironment (TME) trigger signaling pathways in cells that activate cellular programs, resulting in tumor growth and drug resistance. In this review, we describe mechanisms of action for anti-cancer therapies and mechanotransductio...

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Detalles Bibliográficos
Autores principales: Kalli, Maria, Poskus, Matthew D., Stylianopoulos, Triantafyllos, Zervantonakis, Ioannis K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592424/
https://www.ncbi.nlm.nih.gov/pubmed/37558577
http://dx.doi.org/10.1016/j.trecan.2023.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592424/
https://www.ncbi.nlm.nih.gov/pubmed/37558577
http://dx.doi.org/10.1016/j.trecan.2023.07.006

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