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Beyond matrix stiffness: targeting force-induced cancer drug resistance
During tumor progression, mechanical abnormalities in the tumor microenvironment (TME) trigger signaling pathways in cells that activate cellular programs, resulting in tumor growth and drug resistance. In this review, we describe mechanisms of action for anti-cancer therapies and mechanotransductio...
Autores principales: | Kalli, Maria, Poskus, Matthew D., Stylianopoulos, Triantafyllos, Zervantonakis, Ioannis K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10592424/ https://www.ncbi.nlm.nih.gov/pubmed/37558577 http://dx.doi.org/10.1016/j.trecan.2023.07.006 |
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